阿姆斯特丹大学Swammerdam Institute for Life Sciences的分子神经科学研究小组招博士生。有硕士学历，并且有着生物学、生物医学、心理生物学的背景的同学们赶紧看过来哦。申请截止日期是2020年9月14日。详情请参考以下介绍：
 
The Molecular Neuroscience group at the Swammerdam Institute for Life Sciences (SILS) is looking for a motivated PhD student with a strong interest in molecular and developmental neurobiology. During this PhD project you will focus on the role of bHLH transcription factors, specifically Tcf4, in the development of the cortex, medulla and oligodendrocytes in the murine and human brain. Tcf4 is mutated in patients with Pitt-Hopkins Syndrome, and insight in the underlying molecular cascade and subsequent consequences in brain development will help in understanding this developmental disorder. During this PhD project you will research the function of Tcf4 during brain development, especially in regard to patterning, cortical development, and later myelinization.
 
What are you going to do?
As a PhD student you will, together with your (co-)promoter, research the brain development regulated by the bHLH transcription factor Tcf4.
 
You will research:
 
★ the role of Tcf4 during oligodendrogenesis and myelination of the brain;
★ the effect of Tcf4 on development of the medulla and cortex;
★ the development of the human brain under influence of disease-related mutations of Tcf4;
★ which genes are directly regulated by Tcf4;
★ the effects of Tcf4-regulated genes during cortical development.
 
What do we require?
You:
★ have a background (Master) in (psycho)biology of biomedical sciences;
★ are willing to learn and interested in molecular and developmental biology;
★ have significant knowledge of and experience with working in a molecular lab;
★ are capable to proactively and independently work on different research lines;
★ are able to communicate clearly and present in English (both oral and written);
★ preferably have experience with bioinformatics and complex datasets;
★ preferably have an Article 9 certificate and experience with (stem)cell culture.
 
 
Questions?
Do you have questions about this vacancy? Or do you want to know more about our organisation? Please contact:
 
★prof. Marten P. Smidt, Molecular Neuroscience group
+31 (0)20 525 6479
or
★dr Simone Mesman, Molecular Neuroscience group
T: +31 (0)20 525 7055